Inuit youth in Nunavut (NU) are resilient but face a protracted suicide crisis.The SPARX serious game and e-intervention, developed originally in New Zealand, teaches youth cognitive behavioural therapy (CBT) skills to ameliorate stress and depression.Inuit youth in NU reviewed and culturally adapted SPARX and an existing wellness outcome measure f
In the present study, we attempted to control the pH profile of the catalytic activity of the industrially relevant alkaline telemarkskongen flue protease KP-43, by incorporating 3-nitro-l-tyrosine and 3-chloro-l-tyrosine at and near the catalytic site.Thirty KP-43 variants containing these non-natural amino acids at the specific positions were syn
This paper proposes Pomarine jaeger Optimization (PJO) algorithm, Tiger hunting Optimization (THO) Algorithm, Desert Reynard and Vixen Inspired Optimization (DRVIO) Algorithm, Lonchodidae optimization (LO) algorithm, Caracal optimization (CO) algorithm, Barasingha optimization (BO) algorithm, Amur leopard optimization (AO) algorithm and Empress SAR
Summary: Southeast Asia has been the hotbed for the development of drug-resistant malaria parasites, including those with resistance to artemisinin combination therapy.While mutations in the kelch propeller domain (K13 mutations) are associated with artemisinin resistance, a range of evidence suggests that other factors are critical for the establi
In this paper, we evaluate the economic value that arise from incorporating conditional volatility when forecasting the covariance matrix of returns for both short and long horizons in the mg09aca18te Vietnamese stock market, using the volatility timing framework of Fleming et al.(2001).We report three main findings.First, investors are willing to